New yr, new detox, proper? Whether or not it’s inexperienced juices, fasting protocols, or teas that declare to flush you clear, January is once we collectively attempt to undo the indulgences of the previous yr. It feels equal components hopeful and determined—and admittedly, if we’re sincere, doesn’t final lengthy.
We’ve heard these buzzwords earlier than: activated charcoal to “bind toxins,” infrared saunas to “sweat it out,” and dry brushing to “stimulate the lymphatic system.” They every assist the physique’s pure detox pathways—your liver, kidneys, and lymphatic system. However what if there was a solution to take detoxing a step additional? What should you may instantly cleanse virtually all of the blood flowing by way of your physique?
EBO2 or EBOO—brief for Extracorporeal Blood Oxygenation and Ozonation—affords a novel solution to detox—filtering out toxins, heavy metals, built-up lipids, and mobile junk instantly out of your bloodstream. Physicians say it helps goal a number of the root causes of irritation and continual illness.
Once I sat down with Dr. Christopher Davis, an interventional heart specialist with a ardour for well being optimization, his phrases set the stage for our dialog: “We get previous and get sick due to the toxins round us.”
Davis didn’t sugarcoat the truth of contemporary life. Whereas train, vitamin, and stress administration are non-negotiables within the staying wholesome hierarchy, oftentimes our surroundings typically works towards us.
“We’re speaking about heavy metals—mercury, cadmium, lead, arsenic,” he defined. “Add to that pesticides and pesticides like atrazine and DDT. Then there’s plastics—BPA, phthalates, flame retardants, and the nonstick coatings on our cookware. Even the stain-resistant carpets and furnishings in our houses contribute to the poisonous load we stock.”
It’s fairly scary to assume how a lot poisonous chemical compounds we eat, breathe, and drink each day. These substances don’t simply float harmlessly by way of our our bodies, nor do they merely come and go. They accumulate, creating oxidative stress, which over time triggers continual irritation. Davis factors to continual irritation as the basis reason behind many illnesses, together with coronary heart illness, autoimmune problems, Parkinson’s and Alzheimer’s illnesses, and even sure cancers. “Irritation is on the coronary heart of all of it,” he mentioned. “And far of it’s pushed by these toxins.”
Dr. Davis has seen the impression of EBO2, observing vital enhancements in sufferers with autoimmune situations, excessive poisonous hundreds, and even most cancers. Plus, this cutting-edge therapy is gaining traction amongst excessive performers, athletes, and biohackers. Why? For them, optimizing restoration, slowing down getting older, boosting vitality, and counteracting the results of contemporary environmental toxins are high precedence.
Regardless of the thrill, EBO2 just isn’t with out its skeptics. Whereas it’s protected when administered appropriately in a medical setting, the vast majority of the reported advantages are anecdotal, with restricted large-scale medical research to again up its efficacy. As with all new modality, there’s a necessity for extra sturdy, peer-reviewed analysis to find out its long-term results and potential dangers.
What’s EBO2?
Get cozy as a result of this therapy requires you to be hooked to an IV in each arms for 45 minutes whereas roughly 2 to 4 liters of your blood—between 40-80% of your physique’s provide—is drawn, filtered, handled with ozone and particular wavelengths of sunshine, and reintroduced into your physique.
Plus, there’s a container on the aspect the place all of the junk will get filtered into. It seems murky and yellowish, making it onerous to overlook how a lot toxins we stock all through our lives.
Dr. Joseph Purita, a pioneer in regenerative drugs and one of many physicians behind EBO2’s rising recognition within the U.S., describes the method in vivid phrases. “When blood comes out of the physique, it’s darkish. Appears like what we name venous blood. However when it’s filtered and handled with ozone and lightweight, it returns vibrant pink, wanting like arterial blood. It’s virtually as if we had a heart-lung machine oxygenating the blood. But it surely’s not that we’re simply giving oxygen again, as a result of your lungs can try this. There’s quite a lot of attention-grabbing issues which can be occurring, and that’s why I prefer it.”
EBO2 is a comparatively new modality you may discover in a long life, upscale IV, or purposeful drugs clinic with a hefty price ticket starting from $875 to $1,800. And, sadly for a lot of or us, it’s possible an out-of-pocket expense.
The Science Behind EBO2
Davis and Purita defined that EBO2 leverages the physique’s personal mechanisms to heal and create optimistic adaptation by triggering hormesis—a so-called “good stress” by which small quantities of oxidative stress stimulates the physique to adapt. Because the blood flows by way of the dialysis machine it’s uncovered to ozone, a course of that removes toxins, heavy metals, and mobile particles and creates useful oxidative compounds that stimulate your physique’s pure antioxidant defenses, similar to glutathione and superoxide dismutase. As a further step, publicity to particular wavelengths of sunshine—aka photobiomodulation—additional reduces irritation, boosts oxygen supply, and kills dangerous pathogens.
The method is fully exterior, and as Purita emphasised, “ozone is poisonous when inhaled, so no ozone enters the physique. When ozone begins mixing with plasma, it’s transformed instantly to hydrogen peroxide, oxygen, and some different issues.”
Along with cleaning your blood, this course of evokes a number of attention-grabbing mobile mechanisms. Purita added that “EBO2 stimulates pathways like AMPk, which improves vitality effectivity on the mobile stage.”
AMP-activated protein kinase (AMPk) is an enzyme that performs a job in vitality regulation. It acts like a metabolic thermostat, detecting vitality deficits in your cells and triggering mechanisms to revive steadiness. AMPk activation boosts mobile vitality manufacturing and encourages your physique to burn fats for vitality. Plus, research hyperlink AMPk activation to improved mobile restore and diminished getting older markers.
EBO2 upregulates one other key pathway referred to as your physique’s antioxidant powerhouse—the nuclear issue erythroid 2-related issue 2, (NRF2). NRF2 is a transcription issue that regulates the physique’s antioxidant response. Consider it because the grasp regulator of detoxing and irritation management. When activated, NRF2 activates genes that produce antioxidant and anti inflammatory compounds. These might assist the physique remove dangerous substances, cut back oxidative stress, and defend cells from harm attributable to environmental toxins and free radicals.
Dr. Davis famous that this therapy additionally stimulates mitochondrial biogenesis, creating extra of the energy-producing powerhouses inside your cells.
Advantages of EBO2
For athletes, excessive performers, and longevity fans, the advantages of EBO2 can imply quite a lot of issues. Improved oxygen supply and mitochondrial well being translate to raised endurance, sooner restoration, and a sharper thoughts. Decreased irritation and oxidative stress might assist enhance mitochondrial operate (assume extra vitality on the mobile stage). It additionally helps increase your immune system, and improve restoration from exercises or sickness.
Davis defined that extra environment friendly pink blood cell habits additionally results in elevated oxygen supply. “EBO2 improves how pink blood cells move by way of the microvascular system, lowering viscosity and enabling them to maneuver extra effectively,” he mentioned. “The remedy additionally enhances the discharge of oxygen from pink blood cells, making oxygen supply to tissues more practical.”
Moreover, ozone additionally helps stimulate nitric oxide manufacturing, which relaxes blood vessels and will increase blood move, Dr. Davis added. By addressing the mechanics of pink blood cells and their oxygen-releasing capabilities, EBO2 ensures that tissues and organs obtain the oxygen they should carry out optimally.
“Folks will usually have extra vitality, much less mind fog, and only a sense of well-being and vitality,” Davis says, sharing how his sufferers typically describe feeling after a session.
Subjective outcomes usually are not the one ones which will shift. Dr. Davis talked about that there are a selection of biomarkers and goal information he seems at to trace EBO2’s efficacy. “We
can have a look at measures of irritation like CRP, and different markers of oxidative stress,” he added.
Is EBO2 best for you?
EBO2 isn’t a cure-all. Nonetheless, it’s a robust software for these seeking to stage up their detox protocol or handle a continual situation. Additionally it is not one thing you’ll do each week. Dr. Purita defined that until you’ve gotten mildew toxicity, Lyme illness or different autoimmune situation, he’d suggest EBO2 as soon as 1 / 4 or as soon as each six months.
You can contemplate EBO2 if:
- You might be uncovered to excessive ranges of environmental toxins.
- You might be an athlete searching for sooner restoration and higher efficiency.
- You might be targeted on getting older gracefully and sustaining vitality.
Nonetheless, EBO2 might not not appropriate for everybody. Davis and Purita did spotlight that individuals with sure situations, like G6PD deficiency, or these on blood thinners ought to seek the advice of their healthcare supplier earlier than making an attempt EBO2.
One vital consideration each docs identified is that since ozone prompts the AMPk pathway, it mobilizes and pushes glucose into cells. Whereas this can be a optimistic metabolic impact, it could result in a short lived drop in blood sugar through the session.
“As a result of blood sugar can drop through the process, we suggest having a high-carbohydrate meal beforehand,” Purita says. “If blood sugar ranges fall too low through the therapy, we’re ready to deal with it with intravenous glucose to maintain sufferers comfy and protected.”
Davis provides that EBO2 can also be not a standalone answer. Pairing EBO2 with instruments like hyperbaric oxygen remedy, molecular hydrogen, pink gentle remedy, and cryotherapy might create a synergistic impact that may take restoration and efficiency to the subsequent stage. Nonetheless, there’s no one-size-fits-all protocol, and we don’t but know what’s the simplest solution to mix them.
“Everybody’s experimenting,” Dr. Davis famous, “so I’m making an attempt to determine the precise timing to stack all of the modalities.”