Ozone (O3) publicity could cut back the provision of oxygen within the physique, leading to arterial stiffening because of the physique’s pure response to create extra purple blood cells and hemoglobin, in response to a research printed at present in JACC, the flagship journal of the American School of Cardiology.
Researchers discovered that even temporary publicity to elevated ozone ranges lowered blood oxygen saturation, triggered hypoxia-related biomarkers, and elevated arterial stiffness, highlighting the novel connection between ozone publicity and arterial stiffness, demonstrated via complete biomarker evaluation in a high-altitude setting. This research uniquely isolates ozone’s results from different pollution, offering a important step ahead in understanding its unbiased position in cardiovascular damage.”
Dr. Harlan Krumholz, MD, SM, Editor-in-Chief of JACC
Ozone air pollution is changing into a worldwide well being subject. Latest research have linked O3 publicity with an elevated threat of cardiovascular ailments (CVDs), together with ischemic coronary heart illness, stroke, coronary heart failure, and atherosclerosis. Hypoxia, or the deficiency of oxygen within the physique, is acknowledged as a pivotal think about O3-associated CVDs.
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Journal reference:
Hua, Q., et al. (2025) Associations of Brief-Time period Ozone Publicity With Hypoxia and Arterial Stiffness. Journal of the American School of Cardiology. doi.org/10.1016/j.jacc.2024.11.044.